Description
capsules 90 day supply
A cognitive peptide with the boldest promise — synaptogenesis in a single molecule.
Dihexa is a small oral peptide derived from Angiotensin IV. It is one of the most potent neurotrophic compounds known — reported in preclinical research to be far more powerful than BDNF at promoting new synapse formation. Studied primarily for Alzheimer’s disease and cognitive decline, it is used clinically for cognitive enhancement, memory support, and neuroprotection in patients pursuing brain health optimization.
How It Works
- Promotes synaptogenesis — Stimulates formation of new synaptic connections between neurons.
- Activates HGF/c-Met pathway — Uses hepatocyte growth factor signaling for neuroplasticity.
- Crosses the blood-brain barrier — Orally bioavailable and CNS-penetrant.
- Neuroprotective — Protects against neurodegeneration and oxidative damage.
- Memory consolidation — Enhances hippocampal function and long-term memory.
- Highly potent — Reported to be substantially more potent than BDNF in preclinical studies.
What It’s Used For
Cognitive decline: Age-related decline, mild cognitive impairment.
Neurodegeneration: Alzheimer’s disease adjunct, Parkinson’s cognitive symptoms.
Cognitive enhancement: Memory, learning, executive function.
Recovery: Post-concussion syndrome, TBI recovery, stroke recovery.
Neurogenesis support: Formation of new neural connections.
Dosing & Protocol
- Delivery — Oral capsule or sublingual liquid
- Standard dose — 8–25 mg daily, individualized to goals
- Timing — Morning, with or without food
- Cycle — Continuous use or 3–6 month cycles
- Best paired with — Omega-3s, lion’s mane, other neurotrophic support
- Onset — Cognitive effects typically develop over 2–8 weeks
- Administered by — Self-administered at home; prescribed by Dr. Thomas
What Patients Report
- Improved memory recall
- Better learning capacity
- Enhanced mental clarity
- Improved word-finding and verbal fluency
- Better cognitive endurance
- Improved focus on complex tasks
- Reduced brain fog
Safety & Pharmacy Notes
Dihexa is generally well tolerated at therapeutic doses, though it is one of the more powerful peptides in the toolkit.
- Possible mild effects: headache, sleep disturbance if taken late in the day, or occasional overstimulation.
- Long-term human safety data is limited; use is monitored carefully.
- Not recommended in pregnancy, breastfeeding, or active cancer without provider approval.
- Dispensed through licensed 503A compounding pharmacies.
- An initial consultation with Dr. Thomas is required before starting therapy.
